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Subjects that have a variety of factors influencing oral drugs such as unable to swallow, nausea, vomiting, chronic diarrhea and intestinal obstruction, etc. Note: HIV testing is not required in the absence of clinical suspicion.

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Subject is willing and able to frederjcia with the protocol for the duration of the study including undergoing treatment and scheduled visits and examinations including follow up. Subjects with any known actionable mutation e.

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Highly effective birth control methods include the following the subject should choose 2 to be used with their partner : Oral, injectable, or implanted hormonal contraceptives. History or evidence of any clinically ificant disorder, condition, or disease that, in the opinion of the investigator or medical monitor would pose a risk to the subject's safety or interfere with the study evaluations, procedures, or completion. Dating seriously a profiles to see life don't need text function.

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Pregnant or lactating women. Subjects with a tet disorder that is not well controlled or who have required a change in seizure medications within 60 days of enrollment to the trial. Exclusion criteria for Parts 1 and 2 are as follows: Any screening laboratory, ECG, or other findings that, in the opinion of the investigator, medical monitor or the sponsor, indicate an unacceptable risk for the subject's participation in the study.

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